Recombinant IL-4RA (Dupilumab Biosimilar) anticorps

N° du produit ABIN7795142

Cet anticorps Souris Monoclonal détecte spécifiquement IL-4RA (Dupilumab Biosimilar) dans FACS et in vivo. Il présente une réactivité envers Humain.

Aperçu rapide pour Recombinant IL-4RA (Dupilumab Biosimilar) anticorps (ABIN7795142)

Antigène: IL-4RA (Dupilumab Biosimilar)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-4RA (Dupilumab Biosimilar) est non-conjugé

Application: Flow Cytometry (FACS), In vivo Studies (in vivo)

Classe de qualité: Research Grade

Détail du produit anti-IL-4RA (Dupilumab Biosimilar) anticorps

Expression System: Mammalian cells

Fonction: Dupilumab Biosimilar, Endotoxin 0.05 EU/mg

Attributs du produit: What is dupilumab biosimilar research grade? Dupilumab is a monoclonal antibody blocking interleukin 4 and interleukin 13, used for allergic diseases such as eczema (atopic dermatitis), asthma and nasal polyps which result in chronic sinusitis. It is also used for the treatment of eosinophilic esophagitis and prurigo nodularis. Dupilumab binds to the alpha subunit of the interleukin-4 receptor (IL-4Ra), making it a receptor antagonist. Through blockade of IL-4Ra, dupilumab modulates signaling of both the interleukin 4 and interleukin 13 pathways. Dupilumab biosimilar uses the same protein sequences as the therapeutic antibody dupilumab.

Purification: Protein A or G affinity column

Pureté: >95 % by reducing SDS-PAGE

niveau d'endotoxine: Less than 0.5 EU/mg of protein as determined by LAL method

Immunogène: Human IL4R alpha

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: > 3 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Détails sur IL-4RA (Dupilumab Biosimilar)

Antigène: IL-4RA (Dupilumab Biosimilar)

Autre désignation: Dupilumab Biosimilar

Classe de substances: Biosimilar